While Delta Burke has come into and out of the spotlight afforded by television since the 1980s, she's spent a great deal of time and effort off-screen coping with and treating a series of mental health issues. In January 2008, according to ABC News, Burke admitted herself to a psychiatric facility for depression. That topped years of anxiety and panic attacks, which she often endured on the set of "Designing Women," during rehearsals. "My whole body would spasm. It would be very physical, very out of control, jerking," she said, recalling that "[co-star] Meshach Taylor would be holding me and carry me back to my room," while fellow cast member Dixie Carter "would get in the bed and lay beside me and pet me."

Burke also shared that her mental strain from depression and having "to play a character that thought she was so hot" led to suicidal ideation during the run of "Designing Women." After that moment, Burke sought help and was prescribed antidepressants, but she still suffered from depressive bouts before her medications stopped working entirely by early 2008, necessitating the hospital stay, during which time she also received help with hoarding. At the height of her problem, Burke admitted to having crammed 27 storage units so full, there were just "little pathways" through the "stacks" of possessions. "Hoarding's in my genes," Burke later told Psychology Today, adding, "My mother saved the diaper I came home from the hospital in!"

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